[PDF] Aerobic exercise, cognitive behavioural therapy and energy conservation management for multiple sclerosis (MS) fatigue: Are three trials better than one? | Semantic Scholar (2024)

Network meta-analysis showed that balance exercise performed significantly better compared to other exercise and behavioural intervention subtypes, except CBT, which was estimated to be superior to energy conservation and other behavioural interventions.

The Energetic programme could be implemented in different healthcare settings and group settings, and a combination of modules proved to be a facilitator for improving self-management.

Energetic led to sustainable improvements in social participation and functional endurance compared to usual care in patients with NMD and chronic fatigue in this multicenter, assessor-blinded, 2-armed randomized controlled trial with repeated measurements.

The hypothesis is that teleconference and internet versions of the intervention are non-inferior to the traditional mode of clinical service delivery in terms of the primary outcome of self-reported fatigue impact and the secondary outcome of health-related quality of life.

The TREFAMS-ACE programme will provide important insights regarding the most effective treatment for MS-related fatigue and the mechanisms that underlie treatment response and a strong overall meta-analysis.

The individual ECM format used in this study did not reduce MS-related fatigue and restrictions in participation more than an information-only control condition.

Severe MS-related fatigue can be reduced effectively with CBT in the short term, and more research is needed on how to maintain this effect over the long term.

Aerobic training in MS patients with severe fatigue does not lead to a clinically meaningful reduction in fatigue or societal participation when compared to a low-intensity control intervention.

This review evaluated the effectiveness and safety of exercise therapy compared to a no-exercise control condition or another intervention on fatigue, measured with self-reported questionnaires, of people with MS to determine the efficacy and safety.

A fatigue severity scale was internally consistent, correlated well with visual analogue measures, clearly differentiated controls from patients, and could detect clinically predicted changes in fatigue over time and identify features that distinguish fatigue between two chronic medical disorders.

This initial validation study indicates that the FIS has considerable merit as a measure of patient's attribution of functional limitations to symptoms of fatigue.

A fatigue severity scale was internally consistent, correlated well with visual analogue measures, clearly differentiated controls from patients, and could detect clinically predicted changes in fatigue over time and identified features of fatigue that might be characteristic of specific diseases.

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